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US. Department of Transportation – Office of Drug & Alcohol Policy & Compliance (ODAPC)
The Omnibus Transportation Employee Testing Act of 1991 requires drug and alcohol testing of safety-sensitive transportation employees in aviation, trucking, railroads, mass transit, pipelines, and other transportation industries. DOT publishes rules on who must conduct drug and alcohol tests, how to conduct those tests, and what procedures to use when testing. These regulations cover all transportation employers, safety-sensitive transportation employees, and service agents comprising roughly 10 million people. Encompassed in 49 Code of Federal Regulations (CFR) Part 40, the Office of Drug & Alcohol Policy & Compliance (ODAPC) publishes, implements, and provides authoritative interpretations of these rules.

The following links are to various modes of transportation regulated
by the U.S. Department of Transportation:

FMCSA
PHMSA
FRA
FTA
FAA
USCG
Federal Motor Carrier Safety Administration
Pipeline & Hazardous Materials Safety Administration
Federal Railroad Administration
Federal Transit Administration
Federal Aviation Administration
United States Coast Guard

 

Business and Consumer Resources:

NHTSA
SAMHSA
National Highway Transportation & Safety Administration
Substance Abuse and Mental Health Services Administration